• A study by the Mayo Clinic in 2013 found that 70 percent of Americans take at least one prescription drug daily.
  • Pharmacodynamics is a branch of pharmacology that deals with the study of the biochemical and physiological effects of drugs and their mechanisms of action on the body or on microorganisms and other parasites within or on the body.
  • Drugs undergo a long-way road till they release their effect.

We all have taken tablets at some point in our lives for different indications. If we experience a fever or a headache we just take a tablet, and within few hours or a day, we do feel better.

For making us feel better, what actually happens to pills after you swallow them?

 From the mouth, drugs go down through your oesophagus into your stomach or intestine. Some drug's target destination is the stomach, whereas others aim for the small intestines. The pill is covered with some kind of coating, which differs from pill to pill. Depending on the outer surface of Pills they are either dissolved in the stomach or else are transported into the intestines. Special coatings on the pill will either allow the drugs to be absorbed by the stomach lining or the lining of the small intestines. All the components in the pills are absorbed in the intestines and transferred by the blood to the liver. The liver might get affected by pills components. It depends on the components contained in the tablets which determine its harmful effects.

Either way, the medicines will enter the bloodstream at some point. Once in the circulatory system, the drug will be distributed to all tissues and organs, giving its effect.


COPYRIGHT: This article is property of We Speak Science, a nonprofit institution co-founded by Dr. Detina Zalli (Harvard University) and Dr. Argita Zalli (Imperial College London). The article is written by Elona Xhemaili (State University of Tetovo, Master of Pharmaceutical Sciences, Macedonia)